Mỹ Tâm was born in Da Nang, Vietnam, in 1982. She started ballet at the age of six, and continued for three years. She then tried guitar and organ. She enjoyed singing, but did not regard it as a future career. She won first prize in her secondary school’s singing competition, and the Gold Award at Beautiful Voice Spring, the city’s solo singing competition. She was chosen for the Military School of Art in Hanoi; however, because of her family situation, she enrolled in Ho Chi Minh City Conservatory where she studied vocal training.

Mỹ Tâm signed with Vafaco Record in 1999 and participated in many singing bands. She received many awards in various singing competitions. Her first demo song was “Nhé anh” (Please, Dear), written by Nguyen Ha, who helped her build image at the start of her career. She co-wrote a soft ballad, “Mãi yêu” (Endless Love), with Nguyen Quang.

After her contract with Vafaco ended in 2000, she had her hair cut short and colored to a yellow-brown “Korean style”; she also dressed sexier. In 2000, she worked at the Music Center in Ho Chi Minh City. She entered the Asia New Singer Competition that was held in Shanghai, China, and won a bronze medal, which she considered pivotal to becoming a singer. She graduated in 2001 as a top student.

In 2001, Mỹ Tâm released her debut album Mãi Yêu (Endless Love). Her first major hit, “Toc Nau Moi Tram” (Brown Hair, Dark Lips), was an uptempo dance song that inspired a hair dying fad. Her title track established her as a young songwriter. “My Love Candle” and “Yêu Dại Khờ” (Foolish Love) became popular in karaoke establishments. “Hai mươi” (20), written by long-time musician Quốc Bảo, celebrated her twentieth birthday. It described her youthful energy that she brought to life, and became a popular anthem among university women. “Nhé anh” (Please, Dear) was a success, and was followed with a music video; however, the song was hampered by a copyright issue. Endless Love sold 54,000 copies.

In May 2002, she released her first video single, “Hát với Dòng Sông” (Singing with the River). The title song was successful but was criticized for having lazy and incomprehensible lyrics regardless of its catchy tune. The album also included packaged with “Cây Đàn Sinh Viên” (The Guitar of Students). A third track, “Quê Hương Tuổi Thơ Tôi” (Hometown – My Childhood), was initially not a hit because of the overshadowing success of the first two tracks, but eventually became a classic.

Mỹ Tâm released her second studio album, Đâu Chỉ Riêng Em (Not Only Me) in May 2002. The album had more dance-pop than her first album, which was soft R&B, but still had some ballads such as “Khung trời mộng mơ” (Whimsical Sky), “Một lần và mãi mãi” (Once and Forever) and “Ánh Sao Buồn” (Sad Twinkle). “Búp Bê Không Tình Yêu” (Doll Without Love) was a translation of France Gall’s “Poupée de cire, poupée de son”. “Khi xưa ta bé” (When We Were Young) was a translation of Cher’s “Bang Bang (My Baby Shot Me Down)”, but made in an uptempo manner. “Giấc mơ tình yêu” (Love Dream) received airplay on radio and television, and was one of her biggest hits. “Hát Cho Người ở Lại” (Singing for the One who Stayed) also charted well.

In mid 2003, Mỹ Tâm released her third studio album, Yesterday & Now. It contained two of her biggest hits: “Ước gì” (I Wish) and “Họa Mi Tóc Nâu” (Brown-Haired Nightingale). The former became another one of her signature songs, and she performed the song in her television appearances and concerts. The album sold over 60,000 copies within the first few months, and received positive responses from audiences and critics; however, some critics complained that the album lacked coherence and had poor arrangements. The tracks were mostly common ballads, but there were some variants.

In 2004, My Tam held a concert named “Ngày Ấy & Bây Giờ” (Yesterday and Now) in two big stadiums in Vietnam. The total expenditure for the concerts was about 3 billion đồng ($250,000 as of 2003), the most expensive concert funding in the Vietnamese music industry at that time. However, she became the first Vietnamese music artist to have a sold out stadium and her album sold over 100,000 copies, which made it the highest-selling album in Vietnamese recording history. She was recognized as the “Number one pop star in Vietnam” and “Queen of V-Pop.” In 2004, she also held a televised concert “My Childhood Hometown”, and went on a tour called “Live With Your Best”.

On 16 November 2004, she became the first Vietnamese singer to participate in the Asia Song Festival in Seoul, Korea. She sang “Ước gì” (I Wish) and “Nụ hôn bất ngờ” (Surprising Kiss), and received a Plaque of Appreciation and Best Contribution Award from the Korean Minister of Culture and Tourism. She would later collaborate with Korean producers in 2005.

In 2005, she released her fourth studio album, Hoàng Hôn Thức Giấc (The Color of My Life), where she composed many of the songs, such as: “Surprising Kiss”, “Vì đâu” (How Come?), Untold Love, and “Nhớ…” (Remember…). Although it was less successful than her third album, “The Color of My Life” received critical acclaim for its coherence and for her creative control. It eventually sold 20,000 copies. She would later re-release the album with songs from her third album, and a bonus track called “Dường như ta đã” (We Seemed To Be…), which gave the album more of a pop/rock remix feel and contains one of her biggest hits “Dường Như Ta Đã” (We Seemed To Be), composed by her. Then she went on a Power of Dreams tour across different universities

In 2006, Mỹ Tâm worked with Korean Record Narimaru Pictures for her fifth album, Fly. She stated that she was unsatisfied with Vietnamese recording and studio techniques. She also took more vocal training, dance lessons, and expanded her music genres. Instead of her usual pop and ballad style, she added uptempo R&B, hip-hop, and soul songs. Fly was released in December 2006. Many of its tracks were released with music videos: “Hãy đến với em” (Come To Me), “Bí mật” (Secret), and Untold Love? Mỹ Tâm also released a single that contained four re-recorded tracks sung in Korean: “Dường như ta đã” (We Seemed To Be…), “Giọt sương” (The Dew Drop), “Hãy đến với em” (Come To Me), and “Ngày hôm nay” (Today), the last of which was influenced by a R&B track by Alicia Keys. In 2007, she endorsed her first perfume brand called “My Time”, which consists of four scents: passionate, charming, manly, and stylish.

In 2008, as part of her project Thời Gian và Tôi ( The Time and Myself ), She created her own company named Mỹ Tâm Entertainment (MT Entertainment). “Time and Myself”‘s project has been planned to have five albums and a live show, and “is about those who always look back to the past to live a better future”. She released her sixth album, Trở Lại (Come Back), on 17 April. Unlike Fly, the Korean producers were only in charge of recording and mastering the record. All the tracks were composed and handled by Vietnamese producers, including Mỹ Tâm, who produced “Như em dợi anh” (Like I’m Waiting For You). The album title expresses her return to the pop ballad genre with slow-jam and emotional feeling, and has a similar sound to her third album, but with the Korean influence. Come Back brought Mỹ Tâm to a new level in her career: a more professional voice, significantly improved English, and more skilled singing techniques (especially on the R&B track, “Và Em Có Anh” (And I Have You). Although the production is still Vietnamese, it contained a more international vibe, excellent quality, and characterized her as an evolving artist.

On 4 April 2008, Mỹ Tâm established the My Tam (MT) Foundation, a charity that operates on contributions from MT Entertainment, her fans, and others. “Nâng bước ngày mai” (“Sustain the Steps of Tomorrow”) is a prominent, long-term project that has reached cities and regions including Ho Chi Minh City, Huế, Da Nang, Nghệ An, Gia Lai, Bình Định, Phú Yên, Cần Thơ, Đắk Lắk, An Giang and Hà Tĩnh. The project builds houses for the poor, and also has scholarships for the underprivileged. Every year, MT Foundation creates a lot of charity for poor people in the remote area.

In April 2010, Mỹ Tâm released her compilation album, named after her project, Những Giai Điệu Của Thời Gian ( Melodies of Time ) project. In a slideshow article by ABC News (America) in August, she was listed among 12 “ABC’s Global Pop Sensations You’ve Never Heard Of”.

In May 2012, Mỹ Tâm performed at the MTV EXIT concert alongside Simple Plan at the My Dinh Stadium in Ha Noi for the purpose of propaganda against human trafficking. She was appointed MTV EXIT’s representative in Vietnam. On 29 May 2012, Mỹ Tâm was announced to be replacing Siu Black as a judge for the fourth season of Vietnam Idol alongside remaining judges Quốc Trung and Nguyễn Quang Dũng. The season aired in August 2012. Throughout the competition, Mỹ Tâm praised Huong Giang, a top-16 contestant and a transgender woman. “The thing that surprises me is not your voice, it’s your effort,” she said. “Your singing is not absolutely excellent, but your effort makes us want to see how you can improve.” The contestant had previously competed as a male, and the sex change gave her a second chance to compete.

From 2013 and 2014 Mỹ Tâm had been working on her eighth studio album, “Tâm” (self-titled). The album was officially released on 24 March 2013, including 10 original tracks composed by Mỹ Tâm herself and various Korean music producers. The album received positive reviews from critics and was a commercial success overall, with 5,000 copies sold on its first day of release and reaching number one for weeks in a number of downloads on iTunes. In order to promote the album, many music videos have been produced on her official YouTube account, with high interactivity during the release.

On 24 August 2013, Mỹ Tâm set up an acoustic-styled music show called “Send to My Love” in Ho Chi Minh City. She continued to bring the show to Hanoi on 26 October, before hosting a charity event in Da Nang on 16 January 2014. Mỹ Tâm confirmed her return to Vietnam Idol for its fifth season on 21 September. In the celebration ceremony of 2 years MTV Europe Music Award’s establishment on 27 September 2013, My Tam became the first representative of Vietnam to be nominated for the “Best Worldwide Act” award. After lost to Li Yuchun from China, she received the “Outstanding Southeast Asian Artist” trophy from MTV Vietnam representative on the Vietnam Idol stage on 23 March 2014. On 22 October 2013, Mỹ Tâm released a music video for the song “Em phải làm sao”, which received 200,000 views on the day of its publication. After Vietnam Idol wrapped up its fifth season in May 2014, Mỹ Tâm guest judged Your Face Sounds Familiar for a week’s performance show which was broadcast on 7 June. Mỹ Tâm won a VTV Award for the “Outstanding Artist” category on 5 September.

On 28 September 2014, Mỹ Tâm announced her first concert after 10 years- “Heartbeat”, taking place in Ho Chi Minh City and Hanoi, with free ticket. The two concerts attracted approximately 40,000 people at the Military Zone 7 Stadium in Ho Chi Minh City; and about 25,000 audiences at Hang Day Stadium in Hanoi. Her tour was positively received by critics, and brought her a nomination for the 2015 “Tour of the Year” category of the Devotion Award. A DVD which recorded the showcase of Heartbeat in Ho Chi Minh City on 20 April 2015, before the release of the two live shows in Ho Chi Minh City and Hanoi on 22 and 26 April 2015 respectively, to recreate the atmosphere of “Heartbeat” with highlight performances throughout the two shows, had sold 3,600 copies in just 4 hours of debut. The DVD gathered more than 1 billion and 80 million VND as well as reached the milestone of 10,000 copies in a month.

On 12 April 2015, Mỹ Tâm was the last to confirm to become a coach on the third season of The Voice of Vietnam alongside Thu Phương, Tuấn Hưng and Đàm Vĩnh Hưng. Her final contestant, Đức Phúc was crowned the winner on the finale broadcast on 20 September, making Tâm the winning coach on her first attempt as a coach. However, Tâm did not return to The Voice for its fourth season and was replaced by Tóc Tiên. At the VTV Award 2015 took place on 6 September, Mỹ Tâm won the “Artist of the Year” category for the second consecutive time.

From 2016 to 2017, Mỹ Tâm focused on making her ninth album, and release not many music videos like “Đôi mắt màu xanh”, ‘Hãy về với nhau” and “Cuộc tình không may”. On 3 December 2017, Mỹ Tâm released her ninth studio pop soul album, Tâm 9. In the first day release, 5,000 copies of Tâm 9 was sold out in 1 hour. Until now, more than 20,000 CD were sold in Vietnam and became the “best selling album in Vietnam”. On the January 2018, “Tâm 9” has climbed to No. 10 on the Billboard World Albums Chart, making her the first Vietnamese singer to break into the top 10. Also, “Tâm 9” was listed as “best selling album” on ITunes and Amazon. On March 2018, Tâm was honored with the titles of “Singer of the Year” and “Album of the year” (Tam 9) at the Devotion Music Awards 2018.

On 20 October 2018, Tâm’s concert, titled “My Tam, First Love”, was held at the Jangchung Gymnasium in the central of Seoul. It was an important landmark in her career because holding a concert in a foreign country meant meeting regional coverage requirements and having the financial resources to organize it. There were 4000 people attended. After that, she became the first Southeast Asia singer to hold a concert in Jangchung Gymnasium.