Bajwa started her career in Indian soap operas in 2005 with Hari Mirchi Lal Mirchi on DD1 before moving on to Astitva…Ek Prem Kahani on Zee TV followed by Jeet on Star Plus and then Guns and Roses on Star One. She also appeared in the television series CID (CID Special Bureau) as fiancé of ACP Ajatshatru and was also seen in the drama Bone Marrow.

In January 2013, Bajwa appeared in the multi-starer Punjabi film Saadi Love Story, produced by Jimmy Sheirgill productions, directed by Dheeraj Rattan and starring Diljit Dosanjh, Amrinder Gill, and Surveen Chawla. She paired up opposite Diljit Dosanjh again in the film Jatt and Juliet 2 which broke all the previous opening day collection records for Punjabi cinema. In August 2013, her film, Naughty Jatts was released in which she featured along with Binnu Dhillon, Arya Babbar and Roshan Prince. The movie got mixed reviews from critics.

Bajwa married Harry Jawandha in 2015. The couple had their first child in August 2015. In 2020, Bajwa gave birth to twins, both girls.

Bajwa debuted as a director in 2017 with the Punjabi movie Sargi, which stars her sister Rubina Bajwa in the leading role alongside Jassi Gill and Babbal Rai. She also owns a production company called Neeru Bajwa Entertainment. In November 2019, Bajwa starrer and produced film Beautiful Billo went on floors, in which she will be sharing the screen with her sister Rubina Bajwa.