Bharucha began her film career in 2006 with ‘Jai Santoshi Maa’ and then the 2009 film Kal Kissne Dekha. Her next release was Dibakar Banerjee’s suspense film Love Sex Aur Dhokha. In 2011, she appeared in Luv Ranjan’s buddy drama Pyaar Ka Punchnama, featuring an ensemble cast in which she was cast opposite Kartik Aaryan.

Bharucha then starred in Ranjan’s 2013 unsuccessful romantic drama Akaash Vani as the titular female lead opposite Aaryan and Sunny Nijar. Her first film of 2015, Darr @ The Mall opposite Jimmy Sheirgill, was a major box-office disaster. Later that year, she appeared in a sequel to Pyaar Ka Punchnama entitled Pyaar Ka Punchnama 2, which paired her opposite Aaryan again, alongside debutante Sunny Singh Nijjar. It became her first major commercial success, and her second success, earning over ₹880 million (US$12 million) worldwide.

In 2018, Bharucha reunited with Aaryan and Nijjar in Ranjan’s Sonu Ke Titu Ki Sweety, a romantic comedy about a man who tries to separate his friend from his fiancée as he thinks her to be a gold digger. Despite receiving mixed reviews from critics, Sonu Ke Titu Ki Sweety proved to be a blockbuster with domestic earnings of over ₹1.07 billion (US$15 million), and became Bharucha’s first release to enter the 100 Crore Club. It emerged as one of her most successful as well.

As of July 2019, Bharucha has finished work on Hansal Mehta’s social film Chhalaang, in which she is paired opposite Rajkummar Rao for the second time after Love Sex Aur Dhokha, it is produced by Luv Ranjan, Ajay Devgn and Ankur Garg. Chhalaang is set to release on OTT platform Amazon Prime on 13 November 2020 due to covid19 restrictions on movie theatres. Bharucha has been filming Nikhil Nagesh Tiwari’s romantic thriller Hurdang opposite Sunny Kaushal and Vijay Varma produced by Bhushan Kumar for T-Series and Shailesh R Singh for Karma Media and Entertainment.

In October 2020 she filmed a music video with Yo Yo Honey Singh for his single Sayyan Ji at Rajasthan.