In 2005, Monterrey loaned Peralta to Guadalajara as a reinforcement for the 2005 Copa Libertadores tournament. He only played in four matches and did not score any goals.
After his brief loan spell with Guadalajara on 2005, Oribe returns to Guadalajara on 2019 on a permanent deal, after the team signed the veteran forward from rival Club America, generating controversy. The 35-year-old has agreed to a two-year contract with Guadalajara, with the possibility of an extension for a third year. On 1 October, in a Copa MX match against Correcaminos UAT, he would score his first goal after a year-long drought, winning the match 2–0. On 31 January 2020, Peralta scored his first league goal for Guadalajara in a 2–2 draw against Atlético San Luis.
Peralta made his debut for Mexico coming on as a late substitute during a friendly match against Argentina on 9 March 2005. He was included in the preparations for the 2006 World Cup but did not make the final squad.