On 9 January 2014, Mel signed an 18-month contract with West Bromwich Albion of the Premier League. His first match in charge came 11 days later, a 1–1 home draw against Everton.
Mel obtained his first win in English football after seven games, with a 2–1 success at Swansea City on 15 March 2014. On 12 May 2014, one day after the end of the season where he led the Baggies to the 17th place, he left by mutual consent with a record of three wins from 17 games.
Mel returned to former club Betis in December 2014, with a contract lasting until the end of the campaign. He was the April 2015 Segunda División Manager of the Month after his team won all their games, scoring 11 goals and conceding two. On 24 May, after only one loss in his tenure, the league was won as champions and promotion achieved with a 3–0 win over AD Alcorcón.