Hayes may best be remembered for being designated substitute for Arthur Godfrey on both his CBS-TV and radio programs as well as several short-lived television series in which he and Healy co-hosted or co-starred, such as The Peter Lind Hayes Show (1950–51), Star of the Family (1950-1952), and Peter Loves Mary (1960–61). He also appeared on the pilot episode of The Match Game on December 5, 1962. He and his wife Mary were occasional guests on TV quiz shows To Tell the Truth, Password, and What's My Line? In 1964, he appeared in an episode of The Outer Limits, titled "Behold, Eck!", playing the lead role of Dr. Robert Stone, an absent-minded optical engineer and researcher.