Despite a heavy series loss to England, Siddle had another successful match in the Boxing Day Test Match at the Melbourne Cricket Ground, taking 6/75 in an innings loss. Siddle started to enjoy more consistent success, starring against India the next summer with 23 wickets at an average of 18.65. During the series, he took his 100th Test wicket at the SCG on 3 January 2012 and rose to a career-high seventh in the ICC's Test bowler rankings. In the final match of the series he took impressive innings bowling figures of 5/49 on a batting wicket at the Adelaide Oval, even being on a hat-trick at one stage in the match. For this performance he was named the man of the match.
During Australia's tour of the West Indies in early 2012, Siddle suffered another back injury and had to fly home early. Siddle had signed for English county Essex for the 2012 Friends Life t20, England's premier Twenty20 competition, but due to his injury he was unable to fulfill his contract with the club. Siddle returned to the Australian Test team for their series against South Africa at the end of 2012. Whilst out injured, he decided to become a vegetarian. The series was very difficult for Siddle because of the very heavy workload he faced. In the first Test of the series at the Gabba, he was forced to bowl 53 overs in a draw and in the second Test at the Adelaide Oval he bowled 63.5 overs — the most by any Australian fast bowler in a single Test match in the 21st century, as his workload had been compounded by an injury to teammate James Pattinson mid-match. Australia needed to bowl South Africa out in the final two days of the Test match to avoid a second consecutive draw and Siddle was the most successful Australian bowler with four wickets. Whilst showing clear signs of exhaustion throughout the final day, Siddle pushed through and took wickets late in the match but was unable to get Australia the win.
Siddle is a right-arm fast-medium bowler who also bats right-handed. He has primarily been used as a workhorse, bowling for long periods of time, such as bowling the most overs by an Australian fast bowler in a 21st century Test match against South Africa in 2012. His charging run-up and powerful delivery is followed by worrying bounce off the pitch.