She has been married twice. From her first marriage with singer Sakis Galanis has a daughter and the name of the daughter is Rania. In 1992, she met the owner of nightclubs Babis Lazaridis in Germany. They fell madly in love and married in 1999 in Athens. From her second marriage with businessman Babis Lazaridis has a son, the model, journalist and blogger Vasilis Lazaridis. On 13 December 2008, Babis Lazaridis was murdered by unidentified men in the area Voula.

In 2005, Popi Maliotaki signs contract with Alpha Records and released her first album titled Aparetiti Agapi Mou . The music on the album signed by Elias Tryfonides and lyrics by Rania Tikou. Popi Maliotaki and Haris Akritidis they interpret together duet “Aparetiti Agapi Mou”. The song “Me ragises” was distinguished and later shot as video clip with the directorial guidance of the famous director George Gavalos. Although nascent, Popi Maliotaki succeeded with her first personal album to conquer the 13th place for a week in the period 13/6 to 06/19/05 in the official index of the Greek music market of the IFPI TOP 50 songs for the Greek repertoire.

In 2008, after the great success of the third album entitled “Popara”, she collaborated with mobile operator “Helen Q Card” and released calling card with name “Popara” which was the title of their third album. which is the title of the last album.

In 2014, Popi Maliotaki released the single entitled “Ta thelo mou” with music of the single by Panos Roumeliotis and lyrics by Mary Antonaki.

In 2015 she released the single «I epityhia» with lyrics of the single by Popi Maliotaki and music by Panos Roumeliotis, and then she released the single “Ekanes ti diafora” with lyrics by Dimitris Dimitras and music by Panos Roumeliotis from Music Liberty. In 2016 releases her new single entitled “An m’ agapas” with lyrics by Elena Maniati and music by Vangelis Panatos from E & E Music Production. The song “An m’ agapas” visualized shortly after its release by Dimitris Kabas and Maliotaki surprised us in her new clip because in video clip he has participate her son, Vasilis.

In 2018, she signed a contract with the recording company Heaven Music and released the single “De horizoun oi kardies mas” in the lyrics of Panos Falaras and music by Akis Diximos. The video clip is directed by Dimitris Kampas. In May 2019, the song “Thema epafis”, which is in Latin rhythms, was released by Heaven Music. The lyrics bears the signature of Panos Falaras, while the music of Akis Diximos.