Hendrick drove in two races during the 1987 and 1988 Winston Cup Series, with finishes of 33rd and 15th, respectively. He also had a single start in both the Busch Series and the Craftsman Truck Series. He also had been a pit crew member for the Flying 11 that Ray Hendrick (no relation) drove in the 1960s. In 1997, Hendrick began the Hendrick Marrow Program, a non-profit works with the Be The Match Foundation to support the National Marrow Donor Program. It raises funds to add volunteers to the Be The Match Registry, which helps to find a marrow match for patients. It also provides assistance to recipients with uninsured transplant costs. Since the beginning, it has raised millions of dollars, 100,000 potential donors to the organization and eased the financial burden of more the 5,000 patients with grants from the Hendrick Family Fund for Patient Assistance.
In 1997, Hendrick pleaded guilty to mail fraud. In the 1980s, Honda automobiles were in high demand and Honda executives allegedly solicited bribes from dealers for larger product disbursements. Hendrick admitted to giving hundreds of thousands of dollars, BMW automobiles, and houses to American Honda Motor Company executives. Hendrick was sentenced in December 1997 to a $250,000 fine, 12 months' home confinement (instead of prison, due to his leukemia), three years probation, and to have no involvement with Hendrick Automotive Group (which was run by Jim Perkins) or Hendrick Motorsports (run by his brother John) during his year of confinement. In December 2000, Hendrick received a full pardon from President Bill Clinton.