In March 2005, production began on Hamri's first feature, the Focus Features film, Something New, a romantic comedy starring Sanaa Lathan (Brown Sugar, Alien vs. Predator) and Simon Baker (The Ring Two, L.A. Confidential). The film was released on January 29, 2006 and produced by Stephanie Allain through her company, Homegrown Pictures, along with the mini-major Gramercy. The film grossed $11,483,669 million and received generally positive reviews. Cobb described the movie as a "feature film about a black woman, written, directed, and produced by a black woman" which she considered "rare". Hamri's second film as director was 2008's The Sisterhood of the Traveling Pants 2, with America Ferrera, Amber Tamblyn, Alexis Bledel and Blake Lively, which was released on August 6, 2008. The film grossed $44,352,417 and received generally favorable reviews. She went on to direct Just Wright with Queen Latifah and Common, which was released on May 14, 2010. The film grossed $21,570,263 million and received mixed reviews.