He assumed the role of Jack Chesney in Where's Charley? in a concert production as part of New York City Center's Encores! series from March 17–20, 2011. From May 6 through June 19, 2011, took part in the original stage production of A Time to Kill, premiering at the Arena Stage in Washington, D.C., based on the John Grisham novel of the same name; Arcelus originated the role of Jake Brigance. Later that summer, Arcelus filmed and helped produce the independent feature film The Last Day of August, which premiered in October 2012. In November 2011, Arcelus starred in an off-Broadway limited engagement musical production of The Blue Flower at Second Stage, along with Marc Kudisch and Teal Wicks.
In 2012, Arcelus starred in the independent film The Last Day of August. Later that year, he was cast as Lucas Goodwin in the Netflix TV series House of Cards. From 2013 to 2016, he had a recurring role in the show's first, second, and fourth seasons. In 2013, Arcelus reprised his role of Jake Brigance in the Broadway production of A Time To Kill at the Golden Theatre in New York City, which premiered on October 20, 2013.