After Inner Child, Wilson continued to record albums, including 1994's 21… Ways to Grow with producer Rhett Lawrence a Los Angeles session musician and Earth Wind & Fire guitarist Dick Smith. This effort was followed by a move to LaFace Records in 1997, who later released the 1999 album Shanice. While she has not achieved significant commercial success with subsequent albums, she has contributed to various film soundtracks, such as Boomerang ("Don't Wanna Love You") and The Meteor Man ("It's for You"). Wilson also achieved success with her top-ten hit "Saving Forever for You", from the Beverly Hills 90210 Soundtrack. She also recorded "If I Never Knew You", a duet with Jon Secada, for the original soundtrack of Disney's 1995 film Pocahontas.
In addition to singing, Wilson is also an actress, first appearing in season five of Family Matters episode "Rock Enroll". In 1997 she became the first black performer to star in the role of Eponine in the musical Les Misérables on Broadway. In 2001, Shanice made an appearance on her husband Flex's show One on One as a singer also she starred in the made-for-TV movie One Special Moment, an adaptation of Brenda Jackson's 1998 novel of the same name. In 2011, Shanice joined Niecy Nash and Frenchie Davis for the 21st Annual "Divas Simply Singing" HIV/AIDS charity event. Shanice and her husband, Flex, are starring in their own reality show Flex & Shanice, which premiered on November 1, 2014, on OWN.