During his career with Super Junior, Shindong was put into two subgroups, smaller groups that are branched off of the larger Super Junior group. In February 2007, he was placed in the trot-singing Super Junior-T. A year later, he became a member of Super Junior-H.
While Shindong had prior acting experiences as a comedian, his acting debut was in the Super Junior film Attack on the Pin-Up Boys, which premiered on July 26, 2007. In 2008, Shindong played a major supporting role in the mini television series Single Dad in Love and also participated in the drama's original soundtrack. He and radio partner Kim Shin-young appeared in an episode of popular MBC drama Queen of Housewives.
On April 19, 2007, almost two months after Super Junior-T's release of their first single "Rokuko", Leeteuk and Kyuhyun became seriously injured in a car accident, along with Shindong, Eunhyuk, and two managers, when returning home after a recording of the radio show Super Junior Kiss the Radio. While they were on the highway, the front left tire burst as the driver was switching lanes and the van ran into the guard rail/medium on the driver's side and skidded for about 30 metres. At some point, the momentum caused the van to flip over on its right side.