The cartoonist and fine artist Seth in 2003 described Ditko's style as:
Whichever feature he drew, Ditko's idiosyncratic, cleanly detailed, instantly recognizable art style, emphasizing mood and anxiety, found great favor with readers. The character of Spider-Man and his troubled personal life meshed well with Ditko's own interests, which Lee eventually acknowledged by giving the artist plotting credits on the latter part of their 38-issue run. But after four years on the title, Ditko left Marvel; he and Lee had not been on speaking terms for some time, with art and editorial changes handled through intermediaries. The details of the rift remain uncertain, even to Lee, who confessed in 2003, "I never really knew Steve on a personal level." Ditko later claimed it was Lee who broke off contact and disputed the long-held belief that the disagreement was over the true identity of the Green Goblin: "Stan never knew what he was getting in my Spider-Man stories and covers until after [production manager] Sol Brodsky took the material from me ... so there couldn't have been any disagreement or agreement, no exchanges ... no problems between us concerning the Green Goblin or anything else from before issue #25 to my final issues". Spider-Man successor artist John Romita, in a 2010 deposition, recalled that Lee and Ditko "ended up not being able to work together because they disagreed on almost everything, cultural, social, historically, everything, they disagreed on characters. ..." A friendly farewell was given to Ditko in the "Bullpen Bulletins" of comics cover-dated July 1966, including Fantastic Four #52: "Steve recently told us he was leaving for personal reasons. After all these years, we're sorry to see him go, and we wish the talented guy success with his future endeavors."