Leone then appeared in item song Sesamma Bagilu Tegiyamma in Kannada film DK, which marked her debut in Kannada film industry. In April 2015, Leone appeared in Bobby Khan's musical thriller Ek Paheli Leela, where she portrayed dual roles as Leela, a village belle and Meera, a supermodel from Milan. The film was released on April 10, 2015. The film met with mixed to negative reviews but was a commercial success with collections of ₹27.47 crore (US$3.9 million). After a little gap, post the release of Ek Paheli Leela , she appeared in Devang Dholakia's Kuch Kuch Locha Hai was released on May 8, 2015. She essayed the role of a film star opposite Ram Kapoor, Evelyn Sharma and Navdeep Chabbra. The film emerged to be a critical and commercial failure. She did her second Kannada song "Kamakshi" from the film Luv U Alia. Last in 2015, she appeared in a cameo in Akshay Kumar's Singh is Bling. In January 2016, she appeared in Milap Zaveri's adult comedy Mastizaade, released on January 29, 2016 where she portrayed twin sisters, Laila and Lily Lele along with Tusshar Kapoor and Vir Das. The film released to mixed reviews and was an average earner. One critic said "Leone may not be better than this film, but she's the best thing in it." Her next film was Jasmine D'souza's One Night Stand with Tanuj Virwani released on May 6, 2016. The film was released to mixed reviews but was a flop commercially. Her last release of 2016 was Rajeev Chaudary's Beiimaan Love opposite Rajneesh Duggal that released on October 14, 2016. Her performance was widely praised but the film met with negative reviews and flopped. She also appeared in song "Tu Zaroorat Nahi Tu Zaroori Hai" with Sharman Joshi in Fuddu and item song "Choli Blockbuster" for the film Dongri Ka Raja. In December 2016, her song "Laila Main Laila" from Raees with Shah Rukh Khan was released.
A police first information report was filed against her in May 2015 after a woman at Mumbai, India, complained that Leone's website, sunnyleone.com, was destroying the Indian culture. Thane police's cyber cell at Ramnagar booked her for sections 292, 292A, 294 which could land her a term in jail, fine or both. Senior police inspector JK Sawant stated, "We cannot block the website, but will ask the operator to remove objectionable content."