From 1997, Perry presented coverage of BBC Sport’s MotoGP for 13 years. In February 2010, following a year in which she suffered a number of health issues including viral meningitis and an ectopic pregnancy, it was announced that she was stepping down from presenting MotoGP coverage. She stated that the extensive travelling involved combined with her other TV commitments was having a detrimental effect on her work-life balance.

In 1997 Perry married Steve Bullock; their marriage lasted four years. In September 2008, she was engaged to her Dutch boyfriend, Bastien Boosten, whom she met while filming The Gadget Show She suffered a ruptured ectopic pregnancy on 17 February, and was taken to West Middlesex Hospital from her home in Chiswick, where she underwent surgery after losing four pints of blood.

Perry is a patron of Promise Dreams, a charity launched in 2001 and based in her home town of Wolverhampton. Promise Dreams raise money for seriously or terminally ill children, to provide treatment, help and support for them and their families. She also supports @alzheimersuk @wwf Two Wheels For Life, RSPCA and Sport Relief amongst other charities

Since 2004, Perry had been a co-presenter for Channel 5’s The Gadget Show, a hi-tech weekly programme, alongside Jason Bradbury, Jon Bentley, Ortis Deley and Pollyanna Woodward. She was temporarily replaced by Gail Porter while recovering from an ectopic pregnancy, and returned in August 2009. Perry created the current theme music for the Gadget Show in 2011, as part of one of the show’s challenges. In February 2012, it was announced that the show’s format was going to change and be renamed The Gadget Show: World Tour, featuring only two of the previous team of presenters: Jason Bradbury and Pollyanna Woodward.

In 2006, Perry appeared as a celebrity showjumper in the BBC’s Sport Relief event Only Fools on Horses. On 12 July, after being voted off the show, she revealed that she had fallen off her horse 12 times.

On 15 May 2008, Perry appeared on Through the Keyhole on BBC Two, allowing Lisa Snowdon to look around her property before being identified by the panel. In 2010 Perry appeared on ITV’s All Star Mr & Mrs with husband Bastien.

From April 2010, Perry lived in London, but shared a house in the south of France with her fiancé. They married on 6 August 2009, with an Elvis impersonator conducting the 30-minute ceremony. She was the first celebrity bride to post her wedding pictures on Twitter.

On 21 December 2012, the BBC announced that Perry would replace Jake Humphrey as presenter of the BBC’s Grand Prix coverage from the 2013 season, covering 10 live races and 10 highlight shows. She also wrote regular blogs for BBC Sport to give a behind-the-scenes look at F1. This was the first time a woman had taken on the full-time main anchor role in Formula One on British TV.

On 10 March 2012, Perry danced to “Livin’ the Vida Loca” with ex-Gadget Show fellow presenter Ortis Deley for the BBC’s Let’s Dance for Comic Relief. Perry was a guest panellist on the Channel 5 magazine show The Wright Stuff, alongside comedian Lee Hurst, for the week of 19–23 March 2012. Her appearance as a guest in the third series of BBC Two’s The Sarah Millican Television Programme was shown on 2 November 2013. On 14 June 2014, she co-presented the BBC’s coverage of Trooping the Colour with Huw Edwards.

In 2015, it was announced Perry would present a new F1 show for BBC Two with Murray Walker. The show, called Formula 1 Rewind, involves Walker looking back at some of the BBC’s archives.

In March 2016 it was announced that Perry would join BT Sport, presenting the channel’s motorsport content, including the MotoGP World Championship, FIM Speedway and the World Rally Championship. The announcement coincided with the news that UK terrestrial TV coverage of Formula 1 was moving from the BBC to Channel 4.

In September 2016, Perry was made an honorary Doctor of Engineering for services to science, technology, and work encouraging young entrepreneurs.

In 2017, she presented Suzi Perry’s Queens of the Road and Invented in London for BBC One.