The Philadelphia Temperance Society was led not by ministers, as most other temperance societies were, but by doctors who were primarily concerned with the health effects of consuming alcohol. Moving in that company, Graham may have met two of the other fathers of American vegetarianism: William Metcalfe, an English minister who established a vegetarian church in Philadelphia, and William A. Alcott, a Philadelphia doctor who wrote extensively about vegetarianism and wrote the first American vegetarian cookbook. Graham taught himself about physiology and apparently arrived at his own conclusion that meat was just as much an expression of and spur to gluttony as alcohol was, that they corrupted both the body and soul of individuals and harmed families and society. His belief was influenced by the book Treatise on Physiology by François-Joseph-Victor Broussais, published in Philadelphia in 1826, that claimed what people ate had enormous influence on their health. Graham's interest was also captured by the books written by the German chemist, Friedrich Accum, called Treatise on Adulteration of Foods, and Culinary Poisons, in which he denounced the use of chemical additives in food and especially in bread, and Treatise on the Art of Making Good and Wholesome Bread. Wheat flour at that time was often doctored to hide odors from spoilage, to extend it, and to whiten it, and bread was made from very finely ground flour (which Graham viewed as "tortured") and brewers yeast (used to make beer).