Born in San Francisco, Jones graduated from Deer Valley High School in Antioch, California, where he played high school football, in 2007. He was the Contra Costa Times Player of the Year and also earned first team San Francisco Chronicle All-Metro honors as a running back. Jones was also named MVP of the Bay Valley Athletic League and was his team’s MVP on offense. He set his school’s single season record with 19 touchdowns as a two-way starter. He rushed for 1,466 yards (9.3 yards per carry) and 13 touchdowns, and also scored three touchdowns receiving and two on punt returns. On defense, Jones had 37 tackles with a sack and three interceptions. One of his interceptions he returned for a score. He led the Wolverines to a 10-0 regular season record and their first league title.

Jones signed with Eastern Washington in 2007 as a cornerback and was redshirted. Jones started four games at cornerback in 2008 after missing much of the first part of the season with a broken fibula suffered in the first week of preseason practices.

In 2009, Jones was moved to running back, the position he played in high school. Jones scored on an 87-yard run on his first collegiate carry and went on to earn third team All-America honors from both the Associated Press and The Sports Network. He was also a first team All-Big Sky Conference selection. Jones finished with 1,213 rushing yards in 2009 to rank as the sixth-most in school history. He ranked in the top 10 in FCS in rushing (ninth, 101.1 yards per game), scoring (sixth, 9.50 points per game) and all-purpose yards per game (second, 195.4 yards per game). His 2,345 all-purpose yards (rushing, receiving, returns) were the second-most in school history, and his 19 touchdowns and 114 total points both rank fourth. Jones also returned a kickoff 93 yards for a touchdown against Northern Colorado.

In 2013, Raiders general manager Reggie McKenzie stated that Jones will switch from running back to cornerback.

On February 24, 2014, Jones and the Raiders agreed on a three-year contract extension.

On July 28, 2017, Jones was released by the Raiders.

On August 2, 2017, Jones was signed by the Buffalo Bills. He was placed on injured reserve on November 4, 2017, after suffering a broken arm in Week 9.

On March 16, 2018, Jones re-signed with the Bills. He was named a team captain for the 2018 season for his role on special teams. He was placed on injured reserve on October 31, 2018 with a neck injury.

On May 14, 2019, Jones signed with the Houston Texans. His 34-yard reception in overtime set up the Texans’ winning field goal against the Buffalo Bills in the Wild Card Round.

Jones re-signed with the Buffalo Bills on March 30, 2020.