Tomas Venclova was born in Klaipėda in 1937. His father, Antanas, was a poet and Soviet politician. Tomas was educated at Vilnius University. He was one of the five founding members of the Lithuanian Helsinki Group, and took part in Lithuanian and Russian dissident movements. He became friends with poets Anna Akhmatova and Boris Pasternak, as well as Natalya Gorbanevskaya and Joseph Brodsky. In Vilnius, he translated Baudelaire, T.S. Eliot, W.H. Auden, Robert Frost, Osip Mandelstam, Anna Akhmatova, Boris Pasternak, and other authors into Lithuanian. In Lithuania he was forbidden to publish his own work, except in samizdat, although one volume appeared in 1972, entitled A Sign of Speech. In 1977, following his dissident activities, he was forced to emigrate.

He was invited by Czesław Miłosz to teach at the University of California at Berkeley. He did not return to Lithuania until its independence in 1991. Since 1980 he has taught Russian and Polish literature at Yale University.