In 1993, Knight released the album Get Off Mine. According to Knight, the record did not sell well and he disliked performing. According to Shocklee, “One of the reasons why it didn’t catch on was because it was one record that came out of nowhere, and rap is about building momentum.” However, Shocklee is proud of the album, saying, “this record still holds up. You can play it now and it doesn’t sound dated.”

By 2003, Phil Knight became a controlling shareholder in Will Vinton Studios, and Travis Knight was promoted to the board of directors, despite having no management experience himself. Following the departure of Vinton, the Knights began to reorganize the failing studio, which was rebranded as Laika.

Since 2005, Travis Knight has served as Laika’s vice president of animation. He was a producer and lead animator for Coraline (2009), ParaNorman (2012) and The Boxtrolls (2014). He also sits on the Laika board of directors. Along with Anthony Stacchi and Graham Annable, Knight was nominated for Best Animated Feature at the Academy Awards, for The Boxtrolls.

In 2014, Shannon Tindle pitched to Knight a fantasy project based on samurais, which Knight, a fan of fantasy films, approved for development. The film was announced in December, 2014, as Kubo and the Two Strings, while Knight was revealed to be producing and directing the film, marking his directorial debut. The film was released in 2016. Along with Arianne Sutner, Knight was again nominated for Best Animated Feature at the Academy Awards, for Kubo and the Two Strings.

He is the current president and CEO of Laika, along with serving on the board of directors of his father’s company, Nike, Inc., a position he assumed in 2015.

On March 2, 2017, Knight was revealed to be directing the live-action film Bumblebee, a reboot of the Transformers film series, marking Knight’s first time working on a live-action film, and his first time working in a film without acting as a producer. Knight, a fan of the G1 version of the franchise, used many elements from the G1 version in the film. Bumblebee was released in December 21, 2018, to a positive reception from both critics and Transformers fans, with many calling it the best film in the franchise.