Janowicz played college football at Ohio State University. A tailback in the single wing, he won the Heisman Trophy in 1950 as a junior. Woody Hayes, who coached Janowicz’s senior year, said of him, “He was not only a great runner, but also passed, was a placekicker and punter, played safety on defense and was an outstanding blocker. Janowicz epitomized the ‘triple-threat’ football player.”

After college, Janowicz passed up offers to play professional football in order to pursue a baseball career. He reached the major leagues with the Pittsburgh Pirates, but hit only .214 over two seasons as a bench player. He returned to football late in the 1954 season with the Washington Redskins, and was their starting halfback in 1955. During training camp in 1956, he suffered a serious brain injury in an automobile accident that left him partially paralyzed and ended his athletic career.