Yerry Mina

Mina made his Categoría Primera A debut on 15 September 2013, starting in a 0–0 draw at Deportivo Cali. His first professional goal occurred on 18 October, as he scored his team's first in a 2–2 home draw against Atlético Huila.

On 14 December 2013, Mina moved to fellow top tier club Independiente Santa Fe, initially on a one-year loan deal. He made his debut for the club the following 25 January, playing the full 90 minutes in a 3–0 home win against Rionegro.

On 1 May 2016, Mina was confirmed as the new player of Palmeiras, but only joined the club in the following month. He signed a five-year contract with the club eleven days later.

Mina made his debut for the club on 4 July 2016, playing a full game in a 3–1 away defeat of Sport Recife. His first goal for the Verdão arrived in the following fixture, a 1–1 draw against Santos. He was, however, rotated off just before the end of the first half due to an apparent injury. He was carried off the field on a stretcher, in tears. On 13 July it was confirmed that Mina would not recover in time for the 2016 Summer Olympics, with the recuperation from his injury expected to take 6 to 8 weeks.

In 2016, Mina was named to Colombia's Copa América Centenario squad, starting one game against Costa Rica. He played in five of Colombia's 2018 World Cup Qualifying matches from October 2016 to March 2017, and in May 2018 he was named to Colombia's final 23-man squad for the 2018 World Cup in Russia.

On 11 January 2018, FC Barcelona and Palmeiras reached an agreement regarding the transfer of Yerry Mina for the remainder of the current season and five more seasons, until 30 June 2023. This made him the first-ever Colombian to play for the club. The cost of the transfer was €11.8 million, and his release clause was set at €100 million.

On 8 August 2018, Mina signed with Premier League team Everton in a deal worth €30 million.

At the 2018 World Cup, Mina scored three goals for Colombia, all headers. Mina did not play in Colombia's opening 2–1 loss with Japan, but started at centre back in each of Colombia's remaining matches. In the group stage, he scored the opening goal in a 3–0 win over Poland, then scored the lone goal in a 1–0 win over Senegal which propelled Colombia to the top of their group and into the knockout stage. Against England in the round of sixteen, Mina tied the scoring 1–1 in the 93rd minute to send the game into extra time. Colombia went on to lose the game on penalty kicks, ending their tournament. With his three goals, he tied the record number of goals scored by a defender in a single World Cup tournament, sharing the record with Germans Paul Breitner in 1974 and Andreas Brehme in 1990.

He scored his first brace for Everton on 1 February 2020 against Watford at Vicarage Road, scoring them both in stoppage time at the end of the first half in a game that Everton came from 2–0 down to win 2–3.

Mina opened his scoring account for Everton in the 2020–21 season with a bullet header against Brighton in a 4–2 victory at Goodison Park on 3 October 2020.