Young Chris and Neef Buck (born Hanif Muhammad) had been friends since they were young boys on the block (C-Ave). On “Takeover”, a track from his 2001 album The Blueprint, Jay-Z announced the duo as “Chris & Neef”. In 2001, the duo performed on the State Property soundtrack album. Young Chris and Neef starred in the titular movie. Also during this period of their career, Young Chris appeared throughout Dame Dash’s Dream Team compilation, and Beanie Sigel’s The Reason. The duo performed together on guest appearances for albums like Jay-Z’s The Blueprint 2, Freeway’s Philadelphia Freeway, State Property’s The Chain Gang Vol. 2, and Memphis Bleek’s M.A.D.E.; all while recording their album. The Young Gunz scored their first hit with “Can’t Stop, Won’t Stop”, the lead-off single from The Chain Gang Vol. 2 album. Its song and video received major airplay on hip-hop radio, MTV2, and BET and reached #14 on the U.S. Billboard 200 chart and #6 on the Billboard Hot Rap Tracks chart.

In December 2010 Young Chris signed with Division1, a label started by songwriter/producer Rico Love, under the Universal Motown umbrella. Love considers Young Chris his flagship artist, working closely with Young Chris on his debut album and pre-album/mixtape. The mixtape, called “The Re-Introduction”, was released on November 20, 2010. The aptly titled mixtape gives the spotlight to a newly signed Young Chris, as a solo artist, and also, re-introduces the combination of DJ Drama and Don Cannon, the former “Affiliates” partners, hosting their first mixtape together, in several years.

On January 28, a song called “Philly Shit (Mega Mix)” featuring Young Chris, Eve, Black Thought, Money Malc, Fat Joe, Fred The Godson, Diggy Simmons, Jermaine Dupri & The Game was leaked. On March 22, 2011, Young Chris’ single “A$$ets” was commercially released.

On May 6, 2014, he released a mixtape on Datpiff called Gunna Seazon.